Research in the School of Biology spans all scales from single molecules all the way up to ecosystems. Although the bulk of the research is driven by PhD students and postdoctoral fellows, several major and minor projects done by IISER TVM BS-MS routinely translate to publications in peer-reviewed journals co-authored by the students. The following are the broad research areas in the school. You can click through the nodes in the image below, or scroll down for more detailed information.
- Sandhya Ganesan
Host-pathogen Interaction (Biology of infectious diseases, Innate immunity, Cellular defence mechanisms, Intracellular bacterial pathogens, SNARE proteins in immunity) - Ramanathan Natesh
Structural Molecular Biology (Transcription regulation, chaperones and DNA damage repair mechanisms in infectious diseases and cancer using electron cryo microscopy, protein crystallography, bioinformatics and other kindred approaches) - S. Murty Srinivasula
Cell Signalling and Immunity (Cell Signalling, Autophagy, Immunity, Apoptosis, Trafficking and Ubiquitin signalling) - Kamalakannan Vijayan
Immunology and Cell Biology of Parasitic Infections (Host-Parasite interactions, Nutrient trafficking by intracellular parasites, Innate sensing, Immune evasion by parasites, Host-targeted interventions) - V. Stalin Raj
Virology (Emerging infectious disease, Virus discovery, Virus-Host interactions) - Karthik Chandiran
Immunology and Gene regulation (immune response to bacterial and viral infection, t cell differentiation, cell signaling, epigenetics and transcriptomics)
- Ravi Maruthachalam
Plant Molecular Biology (Haploid genetics, Plant centromere biology, Genome instability) - Nishant KT
Genome Stability (DNA repair and recombination, Yeast Genetics, Genome Informatics, Genome stability during mitosis and meiosis) - Ramanathan Natesh
Structural Molecular Biology (Transcription regulation, chaperones and DNA damage repair mechanisms in infectious diseases and cancer using electron cryo microscopy, protein crystallography, bioinformatics and other kindred approaches) - Nishana M
Chromatin Organization (Nuclear organization, Chromatin architecture, Genomic instability, Chromosomal translocations, Chromatin alteration in physiological and diseased conditions) - Sabari Sankar Thirupathy
Molecular Biology (Replication-Transcription Conflicts, DNA Repair & Mutagenesis, Genome Organization, Mechanisms & Evolution of Antibiotic Resistance) - Tapas K Manna
Mammalian Cell Division and Signalling (chromosome segregation, spindle pole biogenesis and signaling in mammalian cells) - N Sadananda Singh
Molecular Genetics (genome editing, adverse drug reaction, Cholesterol metabolism) - Karthik Chandiran
Immunology and Gene regulation (immune response to bacterial and viral infection, t cell differentiation, cell signaling, epigenetics and transcriptomics)
- Sanu Shameer
Systems Biology (cellular metabolism, mathematical models, plant metabolism, parasite metabolism, database management) - Ramanathan Natesh
Structural Molecular Biology (Transcription regulation, chaperones and DNA damage repair mechanisms in infectious diseases and cancer using electron cryo microscopy, protein crystallography, bioinformatics and other kindred approaches) - Tapas K Manna
Mammalian Cell Division and Signalling (chromosome segregation, spindle pole biogenesis and signaling in mammalian cells) - Vijay Jayraman
Protein evolution, Systems biochemistry (evolution of protein complexes, evolution of allostery, effect of allostery on protein promiscuity, engineering gene duplication, role of the iron-sulfur cluster in enzymatic reactions)
- Ullasa Kodandaramaiah
Evolutionary Ecology (Speciation and Diversification, Prey-predator interactions, Coevolution, Phenotypic plasticity, Molecular ecology, Life-history traits) - Hema Somanathan
Behavioural and Evolutionary ecology (Plant-animal mutualisms, Sensory ecology of pollinators, Social spider behaviour) - Anirban Guha
Ecophysiology (photoacclimation and photoprotection, xylem structure and function, climate change and extreme events)
- Nishana M
Chromatin Organization (Nuclear organization, Chromatin architecture, Genomic instability, Chromosomal translocations, Chromatin alteration in physiological and diseased conditions) - Nisha N Kannan
Chronobiology (Circadian pacemaker, sleep, post-transcriptional regulation, memory neuronal circuit, clock and metabolism, evolution of circadian clock) - Jishy Varghese
Developmental Biology (Drosophila development and genetics, insulin signalling in growth and metabolism, inter-organ communication, microRNA functions, cellular and systemic homeostasis) - Satish Khurana
Stem cells and Development (Hematopoietic Stem Cells, Hematopoietic development in the mouse embryo, Bone marrow niche, oxygen sensing mechanism and metabolism, Integrin signaling) - Ravi Maruthachalam
Plant Molecular Biology (Haploid genetics, Plant centromere biology, Genome instability) - Nishant KT
Genome Stability (DNA repair and recombination, Yeast Genetics, Genome Informatics, Genome stability during mitosis and meiosis) - Amrutha Swaminathan
Neurodevelopment (zebrafish behaviour, neurodevelopmental disorders, epilepsy, molecular mechanisms)
- Poonam Thakur
Neurodegeneration Mechanisms (Parkinson's disease, rodent models, electrophysiology, neuroprotection) - Amrutha Swaminathan
Neurodevelopment (zebrafish behaviour, neurodevelopmental disorders, epilepsy, molecular mechanisms) - Swathi Devireddy
Neurobiology of lysosomal storage disorders (lysosomal homeostasis and cell growth in disease mutations of lsds)
